Student Information

Student Name

Nina Latcheva

Email

ninalatcheva@gmail.c

Academy

Engineering

Internship Information

Company/Organization: Columbia Genome Center

Mentor(s):Christine Rupp, Maritza Rosales

Topic of Internship

Genomic Research

Background Information

The Columbia Genome Center is an interdisciplinary center as part of Columbia University which conducts research in the field of genetics. Here, new techniques and technologies are explored to aid studies in biological and biomedical sciences. These technologies are used to study inherited genetic disorders such as depression and Amyotrophic Lateral Sclerosis (ALS). The research projects worked on at the center fall under three major areas: human genetics, technology development and comparative genomics, and the molecular libraries screening center.

Summary of Internship

As an intern at the Columbia Genome Center I was able to gain valuable experience necessary for working in a laboratory. I worked on different projects but primarily on studying current and still-developing DNA and genomic sequencing technologies. I was able to obtain hands-on experience performing genomic techniques such as gel electrophoresis, Polymerase Chain Reaction (PCR), Sanger Sequencing, and Sequencing by Synthesis. Using pipettes and working with sequencing machines and computer programs was also part of my daily routine. I learned about genomic research through discussions with my mentors and reading assignments. Part of my requirements as an intern involved preparing several presentations on what I had learned in order to gain further understanding.

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